nuri77Article The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome Fangrui Zhu,1,2,3,8 Juan Ma,1,2,3,8 Weitao Li,1,2,3,8 Qiannv Liu,1,2,3,8Overview of the antiinflammatory snaling pathway of the orphan nuclear receptor Nur77 in EC. LPS induces an increase of Nur77 expression that negatively regulates endothelial